Dianabol is also capable of interaction with the enzyme aromatase resulting in the possibility of estrogenic side effects. Gynecomastia may become apparent even very early into a cycle, so the user must always ensure that they have the necessary drugs to treat the condition at the earliest possible opportunity. A Selective Estrogen Modulator (SERM) such as Tamoxifen (brand name Nolvadex) is usually used in these instances, perhaps with the addition of an anti-estrogen such as Proviron or Arimidex which will help hinder further estrogenic conversion. (For more information see the article Combating Oestrogens & Progesterone ).
Estrogen side effects because the body aromatises the steroid, Gynecomastia is a constant concern especially when the dosage is high. Water retention can also create a problem by causing the muscle mass to lose definition because of accumulated water and fat. This can be countered by taking an anti-estrogen with the steroid. Methandienone (Dianabol) can have androgenic effects such as oily skin, acne and abnormal hair growth. On the other hand, it has been known to accelerate the process of hair loss and balding. In women, it can create significant masculine effects such as the deepening of the voice and a growth on the face. People prone to these effects should seek a milder alternative such as Deca-Durabolin.