Prednicare steroids for dogs side effects

Adverse reactions (frequency and seriousness):
Anti-inflammatory steroids, such as prednisolone, are known to exert a wide range of side-effects. Whilst single high doses are generally well tolerated, they may induce severe side-effects in long-term use and when esters possessing a long duration of action are administered. Dosage in medium to long term should therefore generally be kept to the minimum necessary to control symptoms. Steroids themselves, during treatment, may cause Cushingoid symptoms involving significant alteration of fat, carbohydrate, protein and mineral metabolism, ., redistribution of body fat, muscle weakness and osteoporosis may result.
During therapy, effective doses suppress the Hypothalamo-Pituitreal-Adrenal axis. Following cessation of treatment, symptoms of adrenal insufficiency extending to adrenocorticol atrophy can arise and this may render the animal unable to deal adequately with stressful situations. Consideration should therefore be given to means of minimising problems of adrenal insufficiency following the withdrawal of treatment, ., dosing on alternate days, dosing to coincide with the endogenous cortisol peak (., in the morning with regard to dogs and in the evening with regard to cats) and a gradual reduction in dosage (for further discussion see standard texts).
Systemically acting corticosteroids may cause polyuria, polydipsia and polyphagia, particularly during the early stages of therapy. Some corticosteroids may cause sodium and water retention and hypokalaemia in long term use. Systemic corticosteroids have caused deposition of calcium in the skin (calcinosis cutis).
Corticosteroids are not recommended for use in pregnant animals. Administration in early pregnancy is known to have caused foetal abnormalities in laboratory animals. Administration in late pregnancy may cause early parturition or abortion.
Corticosteroids may delay wound healing and the immunosuppressant actions may weaken resistance to or exacerbate existing infections. In the presence of bacterial infection, anti-bacterial drug cover is usually required when steroids are used. In the presence of viral infections, steroids may worsen or hasten the progress of the disease.
Gastrointestinal ulceration has been reported in animals treated with corticosteroids and . ulceration may be exacerbated by steroids in patients given non-steroidal anti-inflammatory drugs and in corticosteroid treated animals with spinal cord trauma.
Steroids may cause enlargement of the liver (hepatomegaly) with increased serum hepatic enzymes.

Dosing should be individualized based on disease and patient response:

Initial dose: 5 to 60 mg orally per day; may be give once a day or in divided doses
Maintenance dose: Adjust or maintain initial dose until a satisfactory response is obtained; then, gradually in small decrements at appropriate intervals decrease to the lowest dose that maintains an adequate clinical response

Comments:
-Exogenous corticosteroids suppress adrenocorticoid activity the least when given at the time of maximal activity; consider time of maximal adrenal cortex activity (2 AM to 8 AM) when dosing.
-Alternate day therapy may be considered in patients requiring long-term treatment; it may be necessary to return to a full suppressive daily dose in the event of acute flare-ups.

Uses: As an anti-inflammatory or immunosuppressive agent when corticosteroid therapy is appropriate, such as treatment of certain allergic states; nervous system, neoplastic, or renal conditions; endocrine, rheumatologic, or hematologic disorders; collagen, dermatologic, ophthalmic, respiratory, or gastrointestinal diseases; specific infectious diseases or conditions related to organ transplantation.


For Light items (under 2kg) our standard method is Royal Mail Second Class (there are a few exceptions, so if in doubt check our Delivery page).

To get it faster you can upgrade Light items to Royal Mail 1st Class or a Guaranteed Next Day Courier service, Saturday Courier or even before 12 noon services. There's a small fee, but if you're in a hurry they are worth considering. To qualify for next working day delivery, orders must be placed before 12 Noon Monday to Thursday. There is no standard Saturday courier delivery.

Heavy items weighing 2kg and more are sent via courier. If ordered before noon Monday to Thursday, Heavy items will be delivered next working day. Heavy items ordered after 12 Noon Friday, or anytime Saturday and Sunday will dispatched on Monday for a Tuesday delivery.

Please note that if you are purchasing a mix of Light and Heavy items at the same time, these will be sent separately. The Heavy items being sent by Courier, the Light items by Royal Mail Second Class.

All exceptions to these guidelines are noted in the product description.
For more information, view our Delivery page.

A lot will depend on how stable the vet thinks the cat is on or off meds, and when they last saw her. Legally they have to see the pet every so often to continue to prescribe for her as part of their duty of care - same as a doctor will need to see you every so often for ongoing medications.

Most vets will not post tablets, but there is nothing to stop them posting a written prescription if they do not need to see the cat at a particular time, though you will probably be charged the postage of course! Can you get to your vet in the evening perhaps when maybe someone else is available to mind the baby for you, or at the weekend? If so maybe they will at least supply you with a few tablets to keep you going until you can get her in. We are usually pretty accommodating of that sort of situation provided an appointment is made where a check up is needed.

Veterinary surgeons can charge whatever they want and sometimes their prices are very high. It is true that they cannot perhaps buy in the same bulk as we do, so they have to pay a bit more for their drugs in the first place. They also tend to be reluctant to charge sufficiently for their professional time (because people complain) so they load medication in order to top up some of their income. Our whole business revolves around selling everything as cheaply as we can for a high level of customer service, so our prices are usually much lower. In my view vets should charge for their skills in diagnosing and operating, but leave companies like us to retail the medication and food animals need. We do that side of things much better than them in my view. However if people continue to buy products from their local vet, then they will end up paying more for those things.

Prednicare steroids for dogs side effects

prednicare steroids for dogs side effects

A lot will depend on how stable the vet thinks the cat is on or off meds, and when they last saw her. Legally they have to see the pet every so often to continue to prescribe for her as part of their duty of care - same as a doctor will need to see you every so often for ongoing medications.

Most vets will not post tablets, but there is nothing to stop them posting a written prescription if they do not need to see the cat at a particular time, though you will probably be charged the postage of course! Can you get to your vet in the evening perhaps when maybe someone else is available to mind the baby for you, or at the weekend? If so maybe they will at least supply you with a few tablets to keep you going until you can get her in. We are usually pretty accommodating of that sort of situation provided an appointment is made where a check up is needed.

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prednicare steroids for dogs side effects