An excessive level of corticosteroids may cause Cushing's disease. When a pet is on long-term, high doses of glucocorticoids, there is an increased risk that it will develop a condition called iatrogenic (medication induced) Cushing's disease. The clinical signs of Cushing's disease include increased thirst and urination, an increase in UTI's and skin and ear infections, a "pot-bellied" appearance, thinning skin and hair loss. In the treatment of some diseases, the risk of iatrogenic Cushing's disease is unavoidable. To minimize this risk, corticosteroid doses are tapered down over time, or several different drugs may be used in combination.
CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
Anabolic steroids can cause the development of acne. However, the extent to which it is experienced can be due to a number of varying factors, with the particular steroids and exact dosages used being primary. The skin´s sebaceous glands have a particularly high affinity to Dihydrotestosterone, which is an androgen the body naturally produces from testosterone via the enzyme 5-alpha Reductase. Increased sebaceous gland activity promotes oily skin which can combine with bacteria and dead skin (normal wear and tear) eventually causing pores to become clogged more quickly than the body can cleanse them. This of course, is preventable by using only particular steroids, cleansing the skin regularly, and perhaps using a topical anti-androgen.