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Biologic drugs such as infliximab (Remicade) or infliximab-dyyb (Inflectra), a biosimilar to Remicade, are often prescribed when a person with Crohn's disease does not respond to the standard treatments of 5 ASA-containing drugs, corticosteroids, and immunosuppressants. Infliximab is an antibody that attaches itself to the inflammation-promoting protein, tumor-necrosis factor-alpha (TNF-alpha). Other anti-TNF medications are adalimumab ( Humira ) and adalimumab-atto (Amjevita), a biosimilar to Humira. These drugs are also used to treat other immune system disorders such as rheumatoid arthritis . Certolizumab ( Cimzia ) is another anti-TNF blocker approved for Crohn's disease.

Tbol diarrhea

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