I should have specified that I was referring to Tbols fibrinolytic properties. I've read that it increases clotting time, however I was wondering if there was any studies as to how much the time increase was or how severe the effects are. I am somewhat familiar with fibrinolytic's and their therapeutic use in stroke patients, but not enough to understand how Tbol stacks up. I am considering a low dose (20-40mg) extended run. I am being cautious, possibly overly cautious, as being able to form blood clots is something I thoroughly enjoy being able to do.